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黄芬

发布时间:2015-03-04

 

黄芬博士、副教授、硕士生导师

 

毕业学校:

上海交通大学  

                 

所学专业:

生物医学工程

 

所属教研室:

医学免疫与病原生物学教研室

 

研究方向:

病原生物学

 

在研项目:  

1、  主持国家自然科学基金1项(31360619);

2、主持云南省应用基础研究面上项目2项(2011FZ0682013FB032);

3、  主持云南省教育厅基础研究面上项目1项(2011Y382

4、参与国家自然科学基金面上项目1项(31070132)。

 

研究内容:

从事人兽共患病病原生物学研究,主要研究病毒microRNA与宿主细胞的相互作用关系,针对严重危害人类健康的重大疾病(戊型肝炎病毒)开展不同人群和不同物种的流行病学调查;对戊型肝炎病毒在不同物种之间的跨种间传播机制进行探索;同时利用microRNA建立戊型肝炎病毒体外培养模型并对抗戊型肝炎病毒药物进行筛选研究。

 

所获奖项:

上海市科技进步三等奖

 

发表文章及专利:

1. Huang F, Zhang W, Gong G, Yuan C, Yan Y, Yang S, Cui L, Zhu J, Hua X. Experimental infection of Balb/c nude mice with Hepatitis E virus. BMC Infect Dis. 2009,9:93.

2. Huang F, Hua X, Yang S, Yuan C, Zhang W. Effective inhibition of hepatitis E virus replication in A549 cells and piglets by RNA interference (RNAi) targeting RNA-dependent RNA polymerase. Antiviral Res. 2009, 83(3):274-281.

3. Huang Fen, Junfang Zhou, Zhibiao Yang, Li Cui, Wen Zhang, Congli Yuan, ShixingYanga, JianguoZhua, XiuguoHua, RNA interference inhibits hepatitis E virus mRNA accumulation and protein synthesis in vitro. Vet Microbiol. 2010, 142(3-4): 261-267.

4. Huang F, Yu W, Hua X, Jing S, Zeng W, He Z, Seroepidemiology and Molecular Characterization of Hepatitis E Virus in MacacaMulatta from a Village in Yunnan, China, where Infection with this Virus Is Endemic.Hepat Mon. 2011, 11(9):745-749.

5. Huang F, Wang H, Jing S, Zeng W, Simian foamy virus prevalence in Macacamulatta and zookeepers. AIDS Res Hum Retroviruses. 2012, 28(6): 591-593.

6. Huang F, Ma T, Li L, Zeng W, Jing S*.Low seroprevalence of hepatitis E virus infection in pregnant women in Yunnan, China.Braz J Infect Dis. 2013, 17(6):716-7.

7. Huang F, Yu W, He Z.Foamy virus in the tree shrew Tupaiabelangeri is highly related to simian foamy virus in Macacamulatta.AIDS Res Hum Retroviruses.  2013, 29(8):1177-8.

8. WeikunZeng, Wenhai Yu, Zhanlong He, Shenrong Jing, Fen Huang*. Epidemiology of sporadic cases of human enterovirus 92 in captive primate with acute diarrhea. Jundishapur Journal of Microbiology. 2013, 6(10): e7812.

9. Wenhai Yu, Tianwu Ma, Xianchen Zhao, Zhanlong He, Chenchen Yang, Yanhong Bi, Fen Huang*. Complete genome sequence of swine hepatitis E virus prevalent in the Southwest of China. Genome Announcements. 2014, 2(2): e00090-14. 

10. Zhou J, Huang F, Hua X, Cui L, Zhang W, Shen Y, Yan Y, Chen P, Ding D, Mou J, Chen Q, Lan D, Yang Z, Inhibition of porcine transmissible gastroenteritis virus (TGEV) replication in mini-pigs by shRNA, Virus Res. 2010, 149(1): 51-55.

11. Zhang W, Yang S, Shen Q, Huang F, Shan T, Yang Z, Cui L, Zhu J, Hua X, Genotype 3 hepatitis E virus existed among swine groups in 4 geographically far regions in China, Vet Microbiol. 2010, 140(1-2): 193-195.

 

联系方式

邮箱地址:huangfen6789@163.com