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唐文如

发布时间:2015-03-13

 

唐文如教授、硕士生导师、生物化与分子生物学教研室主任

 

毕业学校:

云南大学  

                 

所学专业:

遗传学

 

所属教研室:

生物化与分子生物学教研室

 

研究方向:

肿瘤表观遗传学

 

主要特长:

遗传学

 

在研项目:  

云南省科技计划项目“ALT肿瘤中p21调控p16去甲基化机制研究”项目主持人

唐文如,2012.10-2015.9(项目编号:2012FB134 )。

 

研究内容:

肿瘤中p16去甲基化的调控机制研究及p53突变状态与化疗药物耐药性相关性,肿瘤个性化治疗研究

 

所获奖项:

云南省自然科学一等奖:基于少数民族DNA库的疾病基因及人群起源的分子遗传研究.肖春杰,俞海菁,宿兵,何黎,胡卫红,唐文如,徐琳,郑冰蓉,李开源,昝瑞光,2007年。

 

发表文章及专利:

(1)    Zhou R, Jia S, Zhao L, Lei W, Luo Y*,Tang W*. Association of Interleukin 1B -511C/T polymorphism with Osteoarthritis, Juvenile Idiopathic Arthritis and Rheumatoid Arthritis susceptibility: a meta-analysis. Gene Ther Mol Biol2013;15:30-67.SCI收录)

(2)    Zhao L, Zhao X, Wu X,Tang W*. Association of p53 Arg72Pro polymorphism with esophageal cancer: a meta-analysis based on 14 case-control studies. Genetic testing and molecular biomarkers2013;17:721-6.SCI收录)

(3)    Yang Z, Nie S, Zhu H, Wu X, Jia S, Luo Y*,Tang W*. Association of p53 Arg72Pro polymorphism with bladder cancer: a meta-analysis. Gene2013;512:408-13.SCI收录)

(4)    Wu X, Wang X, Chan Y, Jia S, Luo Y*,Tang W*. Folate metabolism gene polymorphisms MTHFR C677T and A1298C and risk for Down syndrome offspring: a meta-analysis. European journal of obstetrics, gynecology, and reproductive biology2013;167:154-9.SCI收录)

(5)    Wang SQ, Li J,Tang WR*, Luo Y*. Note of clarification of data in the meta-analysis of XPC 939A>C and 499C>T polymorphisms in skin cancer. Asian Pacific journal of cancer prevention : APJCP2013;14:2687-8.SCI收录)

(6)    Nian Y, Zhu H,Tang WR, Luo Y, Du J, Qiu MH. Triterpenes from the Aerial Parts of Cimicifuga yunnanensis and Their Antiproliferative Effects on p53 Mouse Embryonic Fibroblasts. Journal of natural products201376:896-902.SCI收录)

(7)    Jiang Y, Hou J, Zhang Q, Jia ST, Wang BY, Zhang JH,Tang WR*, Luo Y*. The MTHFR C677T Polymorphism and Risk of Acute Lymphoblastic Leukemia: an Updated Meta-analysis Based on 37 Case-control Studies. Asian Pacific journal of cancer prevention : APJCP2013;14:6357-62.SCI收录)

(8)    Jia S,Tang W, Luo Y. p53 codon 72 polymorphism and hepatocellular carcinoma: a meta-analysis. Hepatology International2013;7:669-75.SCI收录)

(9)    Hou J, Jiang Y,Tang W*, Jia S. p53 codon 72 polymorphism and breast cancer risk: A meta-analysis. Exp Ther Med2013;5:1397-402.SCI收录)

(10)  Zhang X, Wu X,Tang W*, Luo Y*. Loss of p16Ink4a Function Rescues Cellular Senescence Induced by Telomere Dysfunction. Int J Mol Sci2012;13:5866-76.SCI收录)

(11)  Zhang X, Nie S, Si X, Luo Y*,Tang W*. Association between the CTGF -945C/G polymorphism and systemic sclerosis: a meta-analysis. Gene2012;509:1-6.SCI收录)

(12)  Wu X, Zhao L, Zhu H, He D,Tang W*, Luo Y*. Association Between the MTHFR C677T Polymorphism and Recurrent Pregnancy Loss: A Meta-Analysis. Genetic testing and molecular biomarkers2012;16:806-11.SCI收录)

(13)  Wu X, Jia S, Zhang X, Si X,Tang W*, Luo Y*. Two mechanisms underlying the loss of p16(Ink4a) function are associated with distinct tumorigenic consequences for WS MEFs escaping from senescence. Mech Ageing Dev2012;133:549-55.SCI收录)

(14) Tang W, Zhou X, Nie S, Yang Z, Zhu H, Wu X, Zhao R, Luo Y*. Association of p53 Arg72Pro polymorphism with gastric cancer: a meta-analysis. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals2012;17:597-603.SCI收录)

(15) Tang WHe X, Chan Y, Luo Y*. Lack of association between p53 codon 72 polymorphism and endometrial cancer: A meta-analysis. Cancer epidemiology2012;36:e153-e57.SCI收录)

(16)  Si X, Zhang X,Tang W*, Luo Y*. Association between the CTLA-4 +49A/G polymorphism and Graves' disease: A meta-analysis. Experimental and Therapeutic Medicine2012;4:538-44.SCI收录)

(17)  Si X, Zhang X, Luo Y*,Tang W*. Association between the CTLA-4 +49A/G polymorphism and type 1 diabetes: a meta-analysis. Genetic testing and molecular biomarkers2012;16:1336-42.SCI收录)

(18)  Jia S, Zhao L,Tang W*, Luo Y*. The Gain of Function of p53 Mutant p53S in Promoting Tumorigenesis by Cross-talking with H-RasV12. International journal of biological sciences2012;8:596-605.SCI收录)

(19)  Jia S, Xu L, Chan Y, Wu X, Yang S, Yu H, Yang H, Luo Y*,Tang W*. p53 codon 72 polymorphism and endometriosis: a meta-analysis. Archives of gynecology and obstetrics2012;285:1657-61.SCI收录)

(20)  Chan Y, Zi F, Wu X, Ma L, Meng Y, Chen J, Wang S, Luo S, Luo Y*,Tang W*. Note of clarification of data in the meta-analysis of methylenetetrahydrofolate reductase C677T polymorphisms in polycystic ovary syndrome. Molecular human reproduction2012;18:514-5.SCI收录)

(21)  Zhao L, Jia S,Tang W*, Sheng J, Luo Y*. Pu-erh Tea Inhibits Tumor Cell Growth by Down-Regulating Mutant p53. Int J Mol Sci2011;12:7581-93.SCI收录)

(22) Tang W, Zhou X, Chan Y, Wu X, Luo Y*. p53 codon 72 polymorphism and recurrent pregnancy loss: a meta-analysis. Journal of assisted reproduction and genetics2011;28:965-9.SCI收录)

(23)  Li J, Cun Y,Tang WR, Wang Y, Li SN, Ouyang HR, Wu YR, Yu HJ, Xiao CJ. Association of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China. Genetics and molecular research : GMR2011;10:2202-12.SCI收录)

(24)  Cun Y, Li J,Tang W, Sheng X, Yu H, Zheng B, Xiao C. Association of WNK1 exon 1 polymorphisms with essential hypertension in Hani and Yi minorities of China. Journal of genetics and genomics = Yi chuan xue bao2011;38:165-71.SCI收录)

(25) 蔡海强,柳海涛,史斌,李安,唐文如,罗瑛.全基因组扩增技术及其在法医个体识别中的应用.遗传2010;32:1119-25.

(26)  Shou WH, Qiao EF, Wei CY, Dong YL, Tan SJ, Shi H,Tang WR, Xiao CJ. Y-chromosome distributions among populations in Northwest China identify significant contribution from Central Asian pastoralists and lesser influence of western Eurasians. J Hum Genet2010;55:314-22.

(27)  Nie SJ,Tang W(共同第一), Chen B, Li J, Zhang W, Li S, Li W, Yu H, Xiao C. Haplotype-based case-control study of the human AGTR1 gene and essential hypertension in Han Chinese subjects. Clin Biochem2010;43:253-8.

(28) 赵兰君,唐文如,罗瑛. haptoglobin基因型与疟疾发病风险不相关: meta分析.昆明理工大学学报2013;38:65-70.

(29) 苏红,司晓宇,唐文如,罗瑛.失巢凋亡及其在肿瘤侵袭、转移中的调控.遗传2013;35:10-16.

(30)朱晖,李安,余建华,向超杰,苏世达,黄磊,范豫杰,罗瑛,唐文如. p53家族及其通路相关蛋白调节母性生殖的新功能.遗传2012;34:943-49.

 

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